Microbial Minimalism Genome Reduction in Bacterial Pathogens
نویسنده
چکیده
When bacterial lineages make the transition from free-living or facultatively parasitic life cycles to permanent associations with hosts, they undergo a major loss of genes and DNA. Complete genome sequences are providing an understanding of how extreme genome reduction affects evolutionary directions and metabolic capabilities of obligate pathogens and symbionts.
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ورودعنوان ژورنال:
- Cell
دوره 108 شماره
صفحات -
تاریخ انتشار 2002